|
|
2-hydroxybenzoyl-CoA + malonyl-CoA + H+ <=> 4-Hydroxycoumarin + CoA + CO2
|
2.3.1.151
2,3',4,6-tetrahydroxybenzophenone synthase
2.3.1.177
3,5-dihydroxybiphenyl synthase
2.3.1.208
4-hydroxycoumarin synthase
|
–
–
–
|
M
|
|
BRENDA:
BR50286;
BS454957
KEGG:
R10173
MetaCyc:
RXN-11171
SABIO-RK:
14429
|
|
|
|
2-hydroxybenzoyl-CoA + O2 + NADH + H+ <=> 2,5-dihydroxybenzoyl-CoA + NAD+ + H2O
|
1.14.13.209
salicyloyl-CoA 5-hydroxylase
|
–
|
M
|
|
BRENDA:
BR51496
KEGG:
R11056
MetaCyc:
RXN-11740
|
|
|
|
ATP + salicylate + CoA <=> diphosphate + AMP + 2-hydroxybenzoyl-CoA
|
6.2.1.17
propionate---CoA ligase
6.2.1.2
medium-chain acyl-CoA ligase
6.2.1.25
benzoate---CoA ligase
6.2.1.65
salicylate---CoA ligase
|
–
–
–
–
|
|
|
BRENDA:
BR53121
KEGG:
R12642
MetaCyc:
RXN-19845
SABIO-RK:
14154
|
|
|
|
(2-hydroxybenzoyl)adenylate + CoA <=> 2-hydroxybenzoyl-CoA + AMP + H+
|
6.2.1.65
salicylate---CoA ligase
|
–
|
M
|
|
BRENDA:
BR53123
KEGG:
R12641
MetaCyc:
RXN-11739
|
|
|
|
2-hydroxybenzoyl-CoA + H2O <=> H+ + salicylate + CoA
|
3.1.2
3.1.2.20
acyl-CoA hydrolase
3.1.2.23
4-hydroxybenzoyl-CoA thioesterase
3.1.2.28
1,4-dihydroxy-2-naphthoyl-CoA hydrolase
|
–
–
–
–
|
M
|
|
BRENDA:
BS398642
MetaCyc:
RXN-2009
|
|
|
|
2-hydroxybenzoyl-CoA + glycine <=> CoA + N-salicylglycine
|
2.3.1.13
glycine N-acyltransferase
2.3.1.71
glycine N-benzoyltransferase
|
–
–
|
|
|
BRENDA:
BS320421
SABIO-RK:
12951
|
|
|
|
benzoyl-CoA + O2 + reduced_[NADPH-hemoprotein_reductase] <=> 2-hydroxybenzoyl-CoA + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
1.14.14
|
–
|
M
|
|
MetaCyc:
RXN-2008
|
|
|
|
2-hydroxybenzoyl-CoA + anthranilate <=> CoA + N-salicylanthranilate
|
2.3.1.144
anthranilate N-benzoyltransferase
|
–
|
|
|
BRENDA:
BS320522
|
|
|
|
2-hydroxybenzoyl-CoA + glycine <=> CoA + 2-hydroxyhippuric_acid
|
2.3.1.71
glycine N-benzoyltransferase
|
–
|
|
|
BRENDA:
BS435826
|
|
|
|
malonyl-CoA + 2-hydroxybenzoyl-CoA <=> CoA + 2-hydroxybenzoyltriacetic_acid_lactone + CO2
|
2.3.1.177
3,5-dihydroxybiphenyl synthase
|
–
|
|
|
BRENDA:
BS380053
|
|
|
|
2-hydroxybenzoyl-CoA + reduced_methyl_viologen + ATP <=> 2-hydroxy-cyclohexa-1,5-diene-1-carbonyl-CoA + methyl_viologen + ADP + phosphate
|
1.3.7.8
benzoyl-CoA reductase
|
–
|
|
|
BRENDA:
BS371685
|
|